c4Lab Research Map

Ongoing research topics:

  • Personal genome annotation
    • Structural variation (SV) calling
    • Population-specific variant calling
    • Haplotype calling
    • Pharmacogenomics
    • Discovering eQTL-causal variants or pathogenic non-coding variants
  • Automated genome sequencing and annotation pipeline design
    • De novo genome assembly
    • Coding gene prediction and functional annotation
    • Regulatory network construction
      • Predicting transcription factor binding sites (TFBSs)
      • Protein-DNA interaction (binding specificity prediction)
    • Long non-coding RNA (lncRNA) identification and functional annotation